Synthetic Berberine HCL 98% refers to Synthetic Berberine Hydrochloride with a purity of 98%, a high-purity alkaloid raw material produced through chemical synthesis rather than plant extraction. It is widely used in pharmaceuticals, health supplements, and veterinary fields, with stable quality and cost advantages, making it a preferred raw material for large-scale production.
It has the same function with natural Berberine HCL, it improves energy expenditure, reduces body weight, and alleviates nonalcoholic fatty liver disease.
Core Specifications
- English Name: Synthetic Berberine Hydrochloride (Berberine HCl)
- CAS Number: 633-65-8 (Anhydrous); 141433-60-5 (Hydrate)
- Molecular Weight: 371.81
- Appearance: Yellow crystalline powder, odorless, extremely bitter in taste
- Purity: ≥98.0% (Detected by HPLC)
- Solubility: Soluble in hot water, slightly soluble in cold water and ethanol, insoluble in most organic solvents
Pharmaceutical Active Pharmaceutical Ingredient (API)
It has antibacterial and anti-inflammatory effects, and is mainly used in the treatment of intestinal infections such as bacillary dysentery and gastroenteritis. In addition, it can assist in regulating blood sugar, blood lipids, and anti-arrhythmia.
Health Supplement Raw Material
It is processed into capsules or tablets, which are used for weight management and blood sugar and blood lipid regulation, and are popular in the health food market.
Key Differences: Synthetic vs. Natural Extracted
In international trade and procurement, synthetic and natural extracted berberine HCL are two distinct specifications, with the following main differences:
| Items | Synthetic Berberine HCL | Natural Extracted Berberine HCL |
| Source | Complete chemical synthesis (reaction of chemical raw materials) | Extracted from plants such as Coptis chinensis, Phellodendron chinense, and Berberis |
| Purity Requirement | ≥98.0% (higher for pharmacopoeia standards) | ≥97.0% |
| Impurity Control | Includes inspection of synthetic impurities such as cyanide and organic nitriles | Contains plant homologous impurities such as jatrorrhizine and palmatine |
| Heavy Metals | Stricter (≤20 ppm) | Relaxed (≤50 ppm) |
| Price | Lower, stable, suitable for large-scale production | Higher, affected by plant raw material prices |
| Certification | Complies with international pharmacopoeias such as USP/EP/BP | Mostly food grade/health supplement grade |
Q: Are your products tested for quality and purity?
A: Yes, all of our products undergo rigorous testing for quality, purity, and potency. We employ third-party testing laboratories to ensure that our products meet the highest standards of excellence. Additionally, our manufacturing facilities adhere to Good Manufacturing Practices (GMP) to guarantee the quality and safety of our products.
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