About the Company
Proxima ingredients was established in June 2016 with a registered capital of 100 million yuan. It covers a total area of 220 acres and a construction area of 100,000 square meters. It currently has 160 employees and 68 technicians. We have built the marketing exhibition building, research and development center, natural vitamin E basic workshop, high-end workshop, packaging workshop, power workshop, environmental protection workshop, etc. The total construction area is more than 100,000 square meters.
Background
- Tocotrienols provide a significant antioxidant boost protecting cells from oxidative stress and damage
- Tocotrienols support cardiovascular health by reducing cholesterol levels and promoting healthy blood circulation
- They exhibit powerful anti-inflammatory properties that can help alleviate chronic inflammation and related conditions
Global Tocotrienols Market Trends
About Proxima tocotrienols
- Sourced from Palm and Rice Bran—an exclusive source providing the unique mixture of tocotrienols available in oil and powder form.
- Most clinically studied form of tocotrienol
- We offer tocotrienols in the following forms:
- 92% Palm source (oil)
- 50% Palm source (oil)
- 85% Rice source (oil)
- 20% Palm source (powder/oil)
- 30% Palm source (powder/oil)
Proxima tocotrienols Available Forms
Tocotrienols and their sources
- Rich sources
- Palm oil
- Rice Bran
- Nutritional Supplements
- Tocotrienol supplements to meet the requirements
- Incorporate in foods
- Use tocotrienols rich oils for dressings, sauces
Absorption and Bioavailability of Tocotrienols
Tocopherol vs Tocotrienol
| Tocopherol | Comparison | Tocotrienol |
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Tocotrienols in Different Applications
Dosage Recommendations
- Daily Intake – Optimal dose of 100-300 mg/day
- Monitor Effects
- Consistency Matters
- Start Low and Gradual Increase
- Consult HealthCare
- Follow Up
Tocotrienols Supplements: What to Consider?
- Quality
Choose high-quality , third party tested supplements for effectiveness
- Dosage
Consult healthcare professionals for personalized dosage recommendations
- Source
Select tocotrienols derived from natural sources like palm oil and rice bran
- Combination
Consider supplements that include additional antioxidants for enhanced benefits
- Delivery
Capsules
Certification System
The company’s multi-system parallelism, a total of 633 documents at all levels to ensure the effective operation of management activities, and continuous improvement.
- FSSC22000
- Food Safety System Certification
- EUROFINS Non-GMO Food System Certification
- Halal Certificate
- Kosher Certificate
- ISO9001 Quality Management System Certification
- ISO14001 Environmental Management System Certificate
- ISO45001 Occupational Health and Safety Management System Certificate
References
- https://tocotrienol.org/en/brain-health-neuroprotection/
- Tocotrienol’s antioxidant properties protect glial cells, vital for central nervous system health. They do this by neutralizing reactive oxygen species and preserving mitochondrial membrane integrity.
- Upregulation included UCHL1 (ubiquitin-proteasome pathway), CALM1-3 (calcium signaling), ATP5F1A (mitochondrial function), and several tubulins (TUBB, TUBB2B, TUBB3, axonal transport). KEGG pathway analysis showed both treatments affected five major neurodegenerative pathways. The Parkinson’s disease pathway (hsa05012) had the most regulated proteins, suggesting TRF’s neuroprotective effects mimic levodopa.
- The downregulation of HSPA5 (BiP) suggests reduced endoplasmic reticulum stress, while upregulation of heat shock proteins (HSP90AB1, HSPD1) shows enhanced protein folding capacity. The coordinated increase in six tubulin isoforms (TUBA1B, TUBB, TUBB2B, TUBB3, TUBB4B, TUBB6) is noteworthy. These isoforms stabilize microtubules crucial for axonal transport, a process often affected in Parkinson’s disease (Magalingam et al. 2022).
